Increased expression of androgen receptor (AR) in prostate cancer (PC) is associated with transition to androgen independence.Because the progression of PC to advanced stages is often associated with the loss of p53 function, we tested whether the p53 could regulate the expression of AR gene.Here we report that p53 negatively regulates the expressi
Modern vehicles as well as structures consist more and more often of a multi material mix.In addition to the use of light materials (e.g.aluminium) to optimise lightweight construction potential, higher strength alloys are being used more and more frequently.With the different material combinations, the requirements for the joining technology also
The emergence of COVID-19 has displayed the importance of immunization and the need for continued public investment in vaccination programs.Globally, national vaccination programs rely heavily on tax-financed expenditure, requiring upfront investments and ongoing financial commitments.To evaluate annual public investments, jeep liberty fender flare
Background & Aims: HBV-related acute-on-chronic liver failure (HBV-ACLF) is a severe acute liver injury secondary to biomane detangler HBV-related chronic liver disease (with or without cirrhosis) and is characterized by a high short-term mortality rate.Presently, there is a paucity of experimental models that specifically focus on HBV-ACLF bas
According to the latest grid codes, wind turbines (WTs) are required to inject certain amount of reactive and active current into the faulty grid during voltage sags.However, studies have shown that the doubly fed induction generator (DFIG)-based WTs may lose stability under weak grid condition.So the impact biomane detangler of grid code requireme